Manganese toxicity does not cause PD, but may cause a static, unchanging parkinsonism.
The “Parkinson personality” is one of avoiding risk, caffeine, nicotine, and alcoholism, and is often present for many years prior to the onset of the motor symptoms of PD.
PD can occur at any age, but is most common in older people. Based on U.S. Census Bureau count of the number of Mainers over 65 and over 80 in 2015, along with the incidence of PD as people age, one can estimate at least 3500 elderly Mainers currently have PD.
“ON” time is when medications are working and symptoms are lessened.
“OFF” time is when medications are not working and symptoms are present or worse.
