If levodopa is any higher than a low starting dose, it should never be stopped abruptly, but tapered slowly over at least 3 days to minimize risk of very rare, but still very severe, and even possibly life-threatening side effects of rapid withdrawal.
All PD meds should ideally be tapered off, not stopped abruptly, if it is time to stop.
The word Sinemet is a portmanteau built from Latin roots which mean “without vomiting.” Levodopa given without carbidopa may cause nausea and vomiting.
Carbidopa can be prescribed alone if needed to decrease nausea when the amount in Sinemet is not strong enough. It is known by the brand name Lodosyn.
